Catalog Number：RA20251
KV1.3 Rabbit Polyclonal Antibody(A256)
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Size：
50 μL
100 μL
Price：
$149.00
$249.00
Delivery： Order now, ship in 3 days
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| Product Name | KV1.3 Rabbit Polyclonal Antibody(A256) | Species | H,M,R |
| Applications | WB | ||
| Condition | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| Alternative Names | HGK5,KCNA3,MK3,Potassium channel 3,voltage gated potassium channel protein kv1.3 | ||
| Store | Store at -20°C. Stable for one year from the date of shipment. | ||
| Recommended dilutions | WB 1:1,000-2,000 | ||
| Specificity | Antibody can detect endogenous KV1.3 proteins. | ||
| Background | Kv1.3 ( also known as KCNA3, MK3, HGK5, HLK3, PCN3, HPCN3) contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T cell proliferation and activation. Kv1.3 channels are expressed in in various tissues and cell types including brain, vascular smooth muscle cells and leucocytes. Malfunction of Kv1.3 can alter the immune response, elicit neurotoxic effects or impact on cancer growth(PMID: 24305723; 24133455). 14079-1-AP can detect two isoforms of Kv1.3 other than the canonical channel (60 KDa) : A longer isoform (70 KDa) and a truncated isoform (43 KDa). | ||
| Molecular Weight | 64KD | Isotype | IgG |
| GeneID | 3738 | Protein MW | 64KD |
| SWISS | P22001 | Source | Rabbit |
| Antigen | Synthetic Peptide | Category | Polyclonal |
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Western blot analysis of 1)Rat Brain Tissue, 2)Mouse Brain Tissue with KV1.3 Rabbit pAb diluted at 1:2,000.