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Catalog Number:RA20780
Collagen I Polyclonal Antibody
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Size:

50 μL

100 μL

Price:

$149.00

$249.00

Delivery: Order now, ship in 3 days

Product Details
Product Name Collagen I Polyclonal Antibody Species Human;Mouse;Rat
Applications WB;ELISA
Condition Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Alternative Names Collagen alpha-2(I) chain (Alpha-2 type I collagen)
Store Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions WB 1:500-2000, ELISA 1:10000-20000
Specificity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background collagen type I alpha 2 chain(COL1A2) Homo sapiens This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
Molecular Weight 115KD Isotype N/A
GeneID 1278 Protein MW 115
SWISS P08123 Source Rabbit
Antigen Synthesized peptide derived from human Collagen I Polyclonal Category Polyclonal