Size:
50 μg
500 μg
Price:
$704.00
$2464.00
Delivery: Order now, ship in 3 days
Product Name | Recombinant Rat M-CSF | Accesstion Number | Q8JZQ0 |
Alternative Names | Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1 | ||
Description | Recombinant Rat Macrophage Colony-stimulating Factor 1 is produced by our Mammalian expression system and the target gene encoding Glu33-Arg254 is expressed. | ||
Calculated Molecular Weight | Mol Mass:25.2 KDa; APMol Mass:46 KDa, reducing conditions | Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Endotoxin | < 1 EU/µg as determined by LAL test. | Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Biological Activity | N/A | ||
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. | ||
Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. | ||
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. | ||
Background | Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance. |