Catalog Number：RP0019
Recombinant Human IL-1b
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Size：
50 μg
500 μg
Price：
$504.00
$2464.00
Delivery： Order now, ship in 3 days
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| Product Name | Recombinant Human IL-1b | Accesstion Number | P01584 |
| Alternative Names | Interleukin-1 beta; Catabolin; IL1F2; IL1B | ||
| Description | Recombinant Human Interleukin-1 Beta is produced by our E.coli expression system and the target gene encoding Ala117-Ser269 is expressed. | ||
| Calculated Molecular Weight | Mol Mass:17.5 KDa; APMol Mass:17 KDa, reducing conditions | Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB，150 mM NaCl，3% Trehalose，0.02% Tween 80，4% Mannitol，pH 7.4. |
| Endotoxin | < 0.01 EU/µg as determined by LAL test. | Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Biological Activity | Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells. The ED50 for this effect is 20-100 pg/ml. (QC verified) | ||
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. | ||
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. | ||
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. | ||
| Background | IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells. | ||
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Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
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Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells. The ED50 for this effect is 20-100 pg/ml. (QC verified)