Catalog Number：RP0005
Recombinant Human/Murine/Rat BDNF
Copy Product Information
Size：
50 μg
500 μg
Price：
$704.00
$2464.00
Delivery： Order now, ship in 3 days
Manual DownloadProduct Details
| Product Name | Recombinant Human/Murine/Rat BDNF | Accesstion Number | P23560 |
| Alternative Names | Brain-Derived Neurotrophic Factor; BDNF; Abrineurin | ||
| Description | Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed. | ||
| Calculated Molecular Weight | Mol Mass:13 KDa; APMol Mass:14 KDa, reducing conditions | Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
| Endotoxin | < 0.01 EU/µg as determined by LAL test. | Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Biological Activity | N/A | ||
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. | ||
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. | ||
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. | ||
| Background | Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. | ||
-
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
-
Immobilized Human TrkB (C-6His) at 5 μg/mL (100 μL/well) can bind Human/Murine/Rat BDNF: Biotinylated by NHS-biotin prior to testing. The EC50 of Human/Murine/Rat BDNF is ≤20 ng/mL.（QC Verified）