Catalog Number：RA33622
NR0B2 Polyclonal Antibody
Copy Product Information
Size：
50 μL
100 μL
Price：
Inquiry
Inquiry
Delivery： N/A
Product Details
| Product Name | NR0B2 Polyclonal Antibody | Species | Human;Rat;Mouse |
| Applications | WB;ELISA | ||
| Condition | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. | ||
| Alternative Names | |||
| Store | -20°C/1 year | ||
| Recommended dilutions | WB 1:500-2000 ELISA 1:5000-20000 | ||
| Specificity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||
| Background | nuclear receptor subfamily 0 group B member 2(NR0B2) Homo sapiens The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008], | ||
| Molecular Weight | 28KD | Isotype | N/A |
| GeneID | 8431 | Protein MW | 28 |
| SWISS | Q15466 | Source | Rabbit |
| Antigen | Synthesized peptide derived from human protein . at AA range: 30-110 | Category | Polyclonal |