Catalog Number：RA28770
Pin1 Polyclonal Antibody
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Size：
50 μL
100 μL
Price：
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Delivery： N/A
Product Details
| Product Name | Pin1 Polyclonal Antibody | Species | Human;Mouse;Rat |
| Applications | IHC;IF/ICC;ELISA | ||
| Condition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||
| Alternative Names | PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1 | ||
| Store | -20°C/1 year | ||
| Recommended dilutions | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. | ||
| Specificity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||
| Background | peptidylprolyl cis/trans isomerase, NIMA-interacting 1(PIN1) Homo sapiens Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011], | ||
| Molecular Weight | N/A | Isotype | N/A |
| GeneID | 5300 | Protein MW | N/A |
| SWISS | Q13526 | Source | Rabbit |
| Antigen | The antiserum was produced against synthesized peptide derived from human Pin1. AA range:1-50 | Category | Polyclonal |