Catalog Number：RA20650
p53 (phospho Ser15) Polyclonal Antibody
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Size：
50 μL
100 μL
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Product Details
| Product Name | p53 (phospho Ser15) Polyclonal Antibody | Species | Human;Rat |
| Applications | WB;IHC-p;IP;IF/ICC;ELISA | ||
| Condition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||
| Alternative Names | TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53 | ||
| Store | -20°C/1 year | ||
| Recommended dilutions | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. | ||
| Specificity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||
| Background | tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013], | ||
| Molecular Weight | 48 | Isotype | N/A |
| GeneID | 7157 | Protein MW | 48 |
| SWISS | P04637 | Source | Rabbit |
| Antigen | The antiserum was produced against synthesized peptide derived from human p53 around the phosphorylation site of Ser15. AA range:1-50 | Category | Polyclonal |