Catalog Number：RA20324
COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody | Species | H |
| Applications | WB, IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | |||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | WB: 1:1,000 IHC: 1:100 Optimal dilutions should be determined by the end user. | ||
| Specificity | The COX1 Rabbit Polyclonal antibody detects endogenous COX1 proteins. | ||
| Background | Cyclooxygenase-1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described. | ||
| Molecular Weight | ~70KD | Isotype | IgG |
| GeneID | 5742 | Protein MW | 70 |
| SWISS | P23219 | Source | Rabbit |
| Antigen | Synthetic Peptide | Category | Polyclonal |
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Western blot analysis of Hela with COX1 Rabbit Polyclonal antibody diluted at 1:1,000.