Catalog Number：RA20267
CD10 Rabbit Polyclonal Antibody（CD10）
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
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| Product Name | CD10 Rabbit Polyclonal Antibody（CD10） | Species | H, R, M |
| Applications | IHC | ||
| Condition | Antigen Affinity Purified IgG in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | CALLA, Enkephalinase,MME,NEP, Neutral endopeptidase antibody | ||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | IHC: 1:200-500 Optimal dilutions should be determined by the end user. | ||
| Specificity | The CD10 Rabbit Polyclonal Antibody can detects endogenous CD10 proteins. | ||
| Background | CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta. | ||
| Molecular Weight | 85 | Isotype | IgG |
| GeneID | 4311 | Protein MW | 85 |
| SWISS | P08473 | Source | Rabbit |
| Antigen | Recombinant Protein | Category | Polyclonal |
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Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using CD10 Rabbit pAb diluted at 1:500.