Catalog Number：RA10327
CDX2 Mouse Monoclonal Antibody (14H6)
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | CDX2 Mouse Monoclonal Antibody (14H6) | Species | H, M, R |
| Applications | WB, IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | |||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | WB: 1:1000 IHC: 1:200 Optimal dilutions should be determined by the end user. | ||
| Specificity | The CDX2 Mouse Monoclonal antibody detects endogenous CDX2 proteins. | ||
| Background | CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20. | ||
| Molecular Weight | ~42KD | Isotype | IgG1 |
| GeneID | 1045 | Protein MW | 42 |
| SWISS | Q99626 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
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Western blot analysis of 1) 293T, 2)Mouse Heart tissue with CDX2 mAb diluted at 1:2,000.
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IHC staining of human rectal cancer tissue with CDX2 mouse mAb(14H6) diluted at 1:200.