Catalog Number：RA10326
CK16 Mouse Monoclonal Antibody (6F6)
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | CK16 Mouse Monoclonal Antibody (6F6) | Species | H, M, R |
| Applications | IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | |||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | IHC: 1:200 Optimal dilutions should be determined by the end user. | ||
| Specificity | The CK16 Mouse Monoclonal antibody detects endogenous CK16 proteins. | ||
| Background | Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. | ||
| Molecular Weight | ~51KD | Isotype | IgG1 |
| GeneID | 3868 | Protein MW | 51 |
| SWISS | P08779 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
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IHC staining of human gullet cancer tissue with CK16 mouse mAb(6F6) diluted at 1:200.