Size:
50 μL
100 μL
Price:
$198.00
$298.00
Delivery: Order now, ship in 3 days
Product Name | P27 Kip1 Mouse Monoclonal Antibody(1A7) | Species | H, R, M |
Applications | WB | ||
Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
Alternative Names | CDKN1B,CDKN4,Kip1,p27,Cyclin dependent kinase inhibitor 1b | ||
Store | -20°C. Do not aliquot the antibody. | ||
Recommended dilutions | WB: 1:2,000-5,000 Optimal dilutions should be determined by the end user. | ||
Specificity | Antibody can detects endogenous p27 Kip1 protein. | ||
Background | Cyclin dependent kinase inhibitor 1B(CDKN1B) Homo sapiens This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. | ||
Molecular Weight | 27KD | Isotype | IgG1 |
GeneID | 1027 | Protein MW | 27 |
SWISS | P45627 | Source | Mouse |
Antigen | Recombinant Protein | Category | Monoclonal |