Catalog Number：RA10264
TFE3 Mouse Monoclonal Antibody(8B4)
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | TFE3 Mouse Monoclonal Antibody(8B4) | Species | H |
| Applications | IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | BHLHE33; Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33 | ||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | IHC 1:100-200 Optimal dilutions should be determined by the end user. | ||
| Specificity | The antibody detects endogenous TFE3 proteins. | ||
| Background | transcription factor binding to IGHM enhancer 3(TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. | ||
| Molecular Weight | 62KD | Isotype | IgG1 |
| GeneID | 7030 | Protein MW | 62 |
| SWISS | P19532 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Esophageal Squamous Cell Carcinoma Tissue using TFE3 Mouse mAb diluted at 1:200.