Catalog Number：RA20106
β-Catenin Rabbit Polyclonal Antibody
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | β-Catenin Rabbit Polyclonal Antibody | Species | H, R, M |
| Applications | WB, IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082 | ||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | WB: 1:1,000 IHC: 1:500-1,000 Optimal dilutions should be determined by the end user. | ||
| Specificity | The β-Catenin Rabbit Polyclonal antibody detects endogenous β-Catenin proteins. | ||
| Background | The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. | ||
| Molecular Weight | ~92KD | Isotype | IgG1 |
| GeneID | 1499 | Protein MW | 92 |
| SWISS | P35222 | Source | Rabbit |
| Antigen | Recombinant Protein | Category | Polyclonal |
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Western blot analysis of 1) 3T3, 2)Rat Liver, with β-Catenin Rabbit pAb diluted at 1:2,000.
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Immunohistochemical analysis of paraffin-embedded human breast caricnoma using β-catenin Rabbit pAb diluted at 1:500.