Catalog Number：RA10317
NF κB P105P50 Mouse Monoclonal Antibody(4D11)
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | NF κB P105P50 Mouse Monoclonal Antibody(4D11) | Species | H, M |
| Applications | WB | ||
| Condition | Antigen Affinity Purified Rabbit IgG, 1mg/ml in PBS pH7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | NFKB1, nuclear factor nf-kappa-b p105,DNA-binding factor KBF1 | ||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | WB: 1:500-1,000 Optimal dilutions should be determined by the end user. | ||
| Specificity | The Antibody can detects endogenous NF κB P105/P50 proteins. | ||
| Background | Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. | ||
| Molecular Weight | 50,110KD | Isotype | IgG1 |
| GeneID | 4790 | Protein MW | 50110 |
| SWISS | P19838 | Source | Mouse |
| Antigen | Recombinant Protein | Category | Monoclonal |
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Western blot analysis of 1)MCF7 Cell, 2) Mouse Brain Tissue Lysate using NF κB P105/P50 Mouse Monoclonal mAb diluted at 1:1,000.