Size:
50 μL
100 μL
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Product Name | AMPKβ1 Mouse Monoclonal Antibody(5D8) | Species | H, R, M |
Applications | IHC | ||
Condition | Antigen Affinity Purified IgG in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
Alternative Names | AMPK beta 1 antibody,PRKAB1 | ||
Store | -20°C. Do not aliquot the antibody. | ||
Recommended dilutions | IHC: 1:100-200 Optimal dilutions should be determined by the end user. | ||
Specificity | Antibody can detects endogenous AMPKβ1 protein. | ||
Background | Protein kinase AMP-activated non-catalytic subunit beta 1(PRKAB1) Homo sapiens The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. | ||
Molecular Weight | 38KD | Isotype | IgG1 |
GeneID | 5564 | Protein MW | 38 |
SWISS | Q9Y478 | Source | Mouse |
Antigen | Recombinant Protein | Category | Monoclonal |