Size:
50 μL
100 μL
Price:
$198.00
$298.00
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Product Name | CK19 Mouse Monoclonal Antibody (11F5) | Species | H,M,R |
Applications | IHC | ||
Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
Alternative Names | |||
Store | -20°C. Do not aliquot the antibody. | ||
Recommended dilutions | IHC: 1:200 Optimal dilutions should be determined by the end user. | ||
Specificity | The CK19 Mouse Monoclonal antibody detects endogenous CK19 proteins. | ||
Background | This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. | ||
Molecular Weight | ~44KD | Isotype | IgG1 |
GeneID | 3880 | Protein MW | 44 |
SWISS | P08727 | Source | Mouse |
Antigen | Synthetic Peptide | Category | Monoclonal |