Catalog Number：RA10243
CD68 Mouse Monoclonal Antibody (6F3)
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
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| Product Name | CD68 Mouse Monoclonal Antibody (6F3) | Species | H,M,R |
| Applications | IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | |||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | IHC: 1:200 Optimal dilutions should be determined by the end user. | ||
| Specificity | The CD68 antibody detects endogenous CD68 proteins. | ||
| Background | The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. | ||
| Molecular Weight | ~37KD | Isotype | IgG1 |
| GeneID | 968 | Protein MW | 37 |
| SWISS | P34810 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
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IHC staining of human tonsil tissue with CD68 mouse mAb(6F3) diluted at 1:200.