Catalog Number：RA10237
EGFR Mouse Monoclonal Antibody (1B1)
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Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
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| Product Name | EGFR Mouse Monoclonal Antibody (1B1) | Species | H |
| Applications | WB, IF, IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | |||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | WB: 1:1,000 IF: 1:100-200 IHC: 1:100-200 Optimal dilutions should be determined by the end user. | ||
| Specificity | The EGFR Mouse Monoclonal antibody detects endogenous EGFR proteins. | ||
| Background | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. | ||
| Molecular Weight | ~170KD | Isotype | IgG1 |
| GeneID | 1956 | Protein MW | 170 |
| SWISS | P00533 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
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Western blot analysis of Hela with EGFR mAb diluted at 1:1,000.
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Immunohistochemical analysis of paraffin-embedded Human Lung caricnoma using EGFR Mouse mAb diluted at 1:500.