Catalog Number：RA10157
MLKL(Phospho Ser358) Mouse Monoclonal Antibody(6B4)
Copy Product Information
Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
Manual DownloadProduct Details
| Product Name | MLKL(Phospho Ser358) Mouse Monoclonal Antibody(6B4) | Species | H |
| Applications | IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | Mixed lineage kinase domain like protein, FLJ34389 | ||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | IHC: 1:100-200 Optimal dilutions should be determined by the end user. | ||
| Specificity | Antibody can detects endogenous Phospho ser358 MLKL protein. | ||
| Background | Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358. | ||
| Molecular Weight | ~54KD | Isotype | IgG1 |
| GeneID | 197259 | Protein MW | 54 |
| SWISS | Q8NB16 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
-
Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-MLKL S358 Mouse mAb diluted at 1:200.
-
Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Phospho-MLKL S358 Mouse mAb diluted at 1:200.