Catalog Number：RA10011
CD68 Mouse Monoclonal Antibody(12E2)
Copy Product Information
Size：
50 μL
100 μL
Price：
$198.00
$298.00
Delivery： Order now, ship in 3 days
Manual DownloadProduct Details
| Product Name | CD68 Mouse Monoclonal Antibody(12E2) | Species | H, R, M |
| Applications | IHC | ||
| Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Alternative Names | CD68 antigen antibody, Macrophage antigen CD68 (microsialin) antibody, GP110 antibody | ||
| Store | -20°C. Do not aliquot the antibody. | ||
| Recommended dilutions | IHC: 1:200-500 Optimal dilutions should be determined by the end user. | ||
| Specificity | The CD68 antibody can detects endogenous CD68 protein. | ||
| Background | The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. | ||
| Molecular Weight | ~37KD | Isotype | IgG1 |
| GeneID | 968 | Protein MW | N/A |
| SWISS | P34810 | Source | Mouse |
| Antigen | Synthetic Peptide | Category | Monoclonal |
-
Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using CD68 Mouse mAb diluted at 1:500.